The protocol at a glance
There is no medicine dose. Two small human studies tested skin patches that contained acetyl octapeptide-3 together with other ingredients.
| Item | What is known |
|---|---|
| Human dose | Not established |
| Studied in | Skin patches and creams, always with other ingredients |
| Microneedle patch study (24 people) | Patch applied overnight to one eye area; results checked over 28 days |
| Microneedle patch study, 12 weeks | Patch on the eye corner and forearm; number of people not stated in the abstract |
Shin JY et al. Ann Dermatol 2024 and Avcil M et al. J Cosmet Dermatol 2020. Both patches held several actives, so the results cannot be credited to SNAP-8 alone.
We did not capture a community dose. It is described as a cosmetic skin ingredient.
What people say they do, collected from community discussions. Not tested in a trial; shown so you can compare it with the evidence above.
Mixing
No mixing table here: this one is used as a capsule, nasal spray or skin product, or has no human amount to calculate from. The general mixing calculator works for any vial.
What the trials found
No result exists for SNAP-8 alone. Results from patches that contained it among other ingredients:
Shin JY et al. Ann Dermatol 2024 (PMID 39082657); Avcil M et al. J Cosmet Dermatol 2020 (PMID 31134751). Supplier claims of 'up to 63%' wrinkle reduction have no study, size or timeframe attached, so we do not use them.
Side effects
- Both patch studies reported no skin safety problems.
- Safety of SNAP-8 on its own was not tested.
How it works
Cosmetic anti-wrinkle claim
It is marketed to relax the small facial muscles that form expression lines. We did not find a human study that shows this for SNAP-8 alone.
Sources
- Shin JY et al. Ann Dermatol 2024, PMID 39082657
- Avcil M et al. J Cosmet Dermatol 2020, PMID 31134751
- ClinicalTrials.gov search for SNAP-8 / acetyl octapeptide: no studies